Hair Cell Transduction Efficiency of Single- and Dual-AAV Serotypes in Adult Murine Cochleae

Gene delivery is a key component for the treatment of genetic hearing loss. To date, a myriad of adeno-associated virus (AAV) serotypes and surgical approaches have been employed to deliver transgenes to cochlear hair cells, but the efficacy of dual transduction remains unclear. Herein, we investiga...

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Detalles Bibliográficos
Autores principales: Omichi, Ryotaro, Yoshimura, Hidekane, Shibata, Seiji B., Vandenberghe, Luk H., Smith, Richard J.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270144/
https://www.ncbi.nlm.nih.gov/pubmed/32518805
http://dx.doi.org/10.1016/j.omtm.2020.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270144/
https://www.ncbi.nlm.nih.gov/pubmed/32518805
http://dx.doi.org/10.1016/j.omtm.2020.05.007

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