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Decreased cytotoxic T cells and TCR clonality in organ transplant recipients with squamous cell carcinoma

T-cell landscape differences between cutaneous squamous cell carcinoma (cSCC) tumors in immune competent (SCC in IC) and immunocompromised organ transplant recipients (TSCC in OTR) are unclear. We developed an analytical method to define tumor infiltrating lymphocyte (TIL) phenotype in cSCC from imm...

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Detalles Bibliográficos
Autores principales: Frazzette, Nicholas, Khodadadi-Jamayran, Alireza, Doudican, Nicole, Santana, Alexis, Felsen, Diane, Pavlick, Anna C., Tsirigos, Aristotelis, Carucci, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270180/
https://www.ncbi.nlm.nih.gov/pubmed/32550269
http://dx.doi.org/10.1038/s41698-020-0119-9