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Insulin and Exendin-4 Reduced Mutated Huntingtin Accumulation in Neuronal Cells

Patients with diabetes mellitus (DM) are more prone to develop cognitive decline and neurodegenerative diseases. A pathological association between an autosomal dominant neurological disorder caused by brain accumulation in mutated huntingtin (mHTT), known as Huntington disease (HD), and DM, has bee...

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Detalles Bibliográficos
Autores principales: Rea, Silvia, Della-Morte, David, Pacifici, Francesca, Capuani, Barbara, Pastore, Donatella, Coppola, Andrea, Arriga, Roberto, Andreadi, Aikaterini, Donadel, Giulia, Di Daniele, Nicola, Bellia, Alfonso, Lauro, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270204/
https://www.ncbi.nlm.nih.gov/pubmed/32547392
http://dx.doi.org/10.3389/fphar.2020.00779