The role of autophagy in the cytotoxicity induced by trastuzumab emtansine (T-DM1) in HER2-positive breast cancer cells

Trastuzumab emtansine (T-DM1), an antibody–drug conjugate (ADC) of trastuzumab and cytotoxic agent emtansine (DM1), has been approved for the therapy of metastatic HER2-positive breast cancer after prior treatment of trastuzumab and taxane. The impressive efficacy exhibited by T-DM1 has heightened t...

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Detalles Bibliográficos
Autores principales: Liu, Peipei, Fan, Jiajun, Wang, Ziyu, Zai, Wenjing, Song, Ping, Li, Yongping, Ju, Dianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270446/
https://www.ncbi.nlm.nih.gov/pubmed/32495214
http://dx.doi.org/10.1186/s13568-020-01044-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270446/
https://www.ncbi.nlm.nih.gov/pubmed/32495214
http://dx.doi.org/10.1186/s13568-020-01044-0

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