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Strategies for Genetically Engineering Hypoimmunogenic Universal Pluripotent Stem Cells
Despite progress in developing cell therapies, such as T cell or stem cell therapies to treat diseases, immunoincompatibility remains a major barrier to clinical application. Given the fact that a host's immune system may reject allogeneic transplanted cells, methods have been developed to gene...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270609/ https://www.ncbi.nlm.nih.gov/pubmed/32502965 http://dx.doi.org/10.1016/j.isci.2020.101162 |