APOL1 Kidney-Risk Variants Induce Mitochondrial Fission

INTRODUCTION: APOL1 G1 and G2 nephropathy-risk variants cause mitochondrial dysfunction and contribute to kidney disease. Analyses were performed to determine the genetic regulation of APOL1 and elucidate potential mechanisms in APOL1-nephropathy. METHODS: A global gene expression analysis was perfo...

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Detalles Bibliográficos
Autores principales: Ma, Lijun, Ainsworth, Hannah C., Snipes, James A., Murea, Mariana, Choi, Young A, Langefeld, Carl D., Parks, John S., Bharadwaj, Manish S., Chou, Jeff W., Hemal, Ashok K., Petrovic, Snezana, Craddock, Ann L., Cheng, Dongmei, Hawkins, Gregory A., Miller, Lance D., Hicks, Pamela J., Saleem, Moin A., Divers, Jasmin, Molina, Anthony J.A., Freedman, Barry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271005/
https://www.ncbi.nlm.nih.gov/pubmed/32518871
http://dx.doi.org/10.1016/j.ekir.2020.03.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271005/
https://www.ncbi.nlm.nih.gov/pubmed/32518871
http://dx.doi.org/10.1016/j.ekir.2020.03.020

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