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CX3CL1 homo-oligomerization drives cell-to-cell adherence

During inflammatory response, blood leukocytes adhere to the endothelium. This process involves numerous adhesion molecules, including a transmembrane chemokine, CX3CL1, which behaves as a molecular cluster. How this cluster assembles and whether this association has a functional role remain unknown...

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Detalles Bibliográficos
Autores principales: Ostuni, Mariano A., Hermand, Patricia, Saindoy, Emeline, Guillou, Noëlline, Guellec, Julie, Coens, Audrey, Hattab, Claude, Desuzinges-Mandon, Elodie, Jawhari, Anass, Iatmanen-Harbi, Soria, Lequin, Olivier, Fuchs, Patrick, Lacapere, Jean-Jacques, Combadière, Christophe, Pincet, Frédéric, Deterre, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271195/
https://www.ncbi.nlm.nih.gov/pubmed/32494000
http://dx.doi.org/10.1038/s41598-020-65988-w