RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro

Fat distribution is an independent cardiometabolic risk factor. However, its molecular and cellular underpinnings remain obscure. Here we demonstrate that two independent GWAS signals at RSPO3, which are associated with increased body mass index-adjusted waist-to-hip ratio, act to specifically incre...

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Detalles Bibliográficos
Autores principales: Loh, Nellie Y., Minchin, James E. N., Pinnick, Katherine E., Verma, Manu, Todorčević, Marijana, Denton, Nathan, Moustafa, Julia El-Sayed, Kemp, John P., Gregson, Celia L., Evans, David M., Neville, Matt J., Small, Kerrin S., McCarthy, Mark I., Mahajan, Anubha, Rawls, John F., Karpe, Fredrik, Christodoulides, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271210/
https://www.ncbi.nlm.nih.gov/pubmed/32493999
http://dx.doi.org/10.1038/s41467-020-16592-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271210/
https://www.ncbi.nlm.nih.gov/pubmed/32493999
http://dx.doi.org/10.1038/s41467-020-16592-z

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