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Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici

Uridine phosphorylase (UP) is a key enzyme of pyrimidine salvage pathways that enables the recycling of endogenous or exogenous-supplied pyrimidines and plays an important intracellular metabolic role. Here, we biochemically and structurally characterized two evolutionarily divergent uridine phospho...

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Detalles Bibliográficos
Autores principales: Yang, Cancan, Li, Jing, Huang, Zhenling, Zhang, Xuefa, Gao, Xiaolei, Zhu, Chunyuang, Morris, Paul F., Zhang, XiuGuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271239/
https://www.ncbi.nlm.nih.gov/pubmed/32493959
http://dx.doi.org/10.1038/s41598-020-65935-9