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Sitagliptin and the Blood-Retina Barrier: Effects on Retinal Endothelial Cells Manifested Only after Prolonged Exposure

Inhibitors of dipeptidyl peptidase-4 (DPP-4) are widely used to treat diabetes mellitus, but data concerning their effects on the barrier stability of retinal endothelial cells (REC) in vivo and in vitro are inconsistent. Therefore, we studied whether the barrier properties of immortalized endotheli...

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Detalles Bibliográficos
Autores principales: Jäckle, Anja, Ziemssen, Focke, Kuhn, Eva-Maria, Kampmeier, Jürgen, Lang, Gerhard K., Lang, Gabriele E., Deissler, Helmut, Deissler, Heidrun L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271241/
https://www.ncbi.nlm.nih.gov/pubmed/32566677
http://dx.doi.org/10.1155/2020/2450781