Cargando…

HEATR1 Deficiency Promotes Chemoresistance via Upregulating ZNF185 and Downregulating SMAD4 in Pancreatic Cancer

OBJECTIVE: To discover the correlated gene with HEATR1 in regulating chemoresistance of gemcitabine. METHODS: Gene chip analysis was performed to find out differential genes between HEATR1-KD and control groups. The top 20 genes were subjected to high-content screening, and functional assay was impl...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Yuan, Han, Xu, Li, Jianang, Kuang, Tiantao, Lou, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271247/
https://www.ncbi.nlm.nih.gov/pubmed/32565799
http://dx.doi.org/10.1155/2020/3181596