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Gilteritinib in the treatment of relapsed and refractory acute myeloid leukemia with a FLT3 mutation
Acute myeloid leukemia (AML) is a malignancy of uncontrolled proliferation of immature myeloid blasts characterized by clonal evolution and genetic heterogeneity. FMS-like tyrosine kinase 3 (FLT3) mutations occur in up to a third of AML cases and are associated with highly proliferative disease, sho...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271272/ https://www.ncbi.nlm.nih.gov/pubmed/32547718 http://dx.doi.org/10.1177/2040620720930614 |