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Gilteritinib in the treatment of relapsed and refractory acute myeloid leukemia with a FLT3 mutation

Acute myeloid leukemia (AML) is a malignancy of uncontrolled proliferation of immature myeloid blasts characterized by clonal evolution and genetic heterogeneity. FMS-like tyrosine kinase 3 (FLT3) mutations occur in up to a third of AML cases and are associated with highly proliferative disease, sho...

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Detalles Bibliográficos
Autores principales: Chew, Serena, Mackey, Melissa C., Jabbour, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271272/
https://www.ncbi.nlm.nih.gov/pubmed/32547718
http://dx.doi.org/10.1177/2040620720930614