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RAD54 promotes alternative lengthening of telomeres by mediating branch migration

Cancer cells can activate the alternative lengthening of telomeres (ALT) pathway to promote replicative immortality. The ALT pathway promotes telomere elongation through a homologous recombination pathway known as break‐induced replication (BIR), which is often engaged to repair single‐ended double‐...

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Detalles Bibliográficos
Autores principales: Mason‐Osann, Emily, Terranova, Katherine, Lupo, Nicholas, Lock, Ying Jie, Carson, Lisa M, Flynn, Rachel Litman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271314/
https://www.ncbi.nlm.nih.gov/pubmed/32337843
http://dx.doi.org/10.15252/embr.201949495