The fiber metabolite butyrate reduces gp130 by targeting TRAF5 in colorectal cancer cells

BACKGROUND: Dietary fiber is effective for colorectal cancer (CRC) treatment. Interleukin-6 (IL-6) and its adaptors are potential targets for CRC therapy. Butyrate, a metabolite of dietary fiber, is a new, highly safe type of targeted drug. METHODS: In this study, Cell Counting Kit-8 cell viability...

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Detalles Bibliográficos
Autores principales: Yuan, Yin, Li, Bo, Kuang, Yanbin, Ni, Shuo, Zhuge, Aoxiang, Yang, Jing, Lv, Longxian, Gu, Silan, Yan, Ren, Li, Yating, Wang, Kaicen, Yang, Liya, Zhu, Xueling, Wu, Jingjing, Bian, Xiaoyuan, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271451/
https://www.ncbi.nlm.nih.gov/pubmed/32518521
http://dx.doi.org/10.1186/s12935-020-01305-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271451/
https://www.ncbi.nlm.nih.gov/pubmed/32518521
http://dx.doi.org/10.1186/s12935-020-01305-9

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