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Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies and correlation with FLT3 mutations and polyunsaturated fatty acid metabolism

Obesity correlates with hematologic malignancies including leukemias, but risk of specific leukemia subtypes like acute promyelocytic leukemia and underlying molecular mechanisms are poorly understood. We explored multiple datasets for correlation between leukemia, body mass index (BMI) and molecula...

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Detalles Bibliográficos
Autores principales: Mazzarella, Luca, Botteri, Edoardo, Matthews, Anthony, Gatti, Elena, Di Salvatore, Davide, Bagnardi, Vincenzo, Breccia, Massimo, Montesinos, Pau, Bernal, Teresa, Gil, Cristina, Ley, Timothy J, Sanz, Miguel, Bhaskaran, Krishnan, Coco, Francesco Lo, Pelicci, Pier Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271575/
https://www.ncbi.nlm.nih.gov/pubmed/31515354
http://dx.doi.org/10.3324/haematol.2019.223925