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Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy

Multiple myeloma is a malignant plasma-cell disease, which is highly dependent on the hypoxic bone marrow microenvironment. However, the underlying mechanisms of hypoxia contributing to myeloma genesis are not fully understood. Here, we show that long non-coding RNA DARS-AS1 in myeloma is directly u...

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Detalles Bibliográficos
Autores principales: Tong, Jia, Xu, Xiaoguang, Zhang, Zilu, Ma, Chengning, Xiang, Rufang, Liu, Jia, Xu, Wenbin, Wu, Chao, Li, Junmin, Zhan, Fenghuang, Wu, Yingli, Yan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271587/
https://www.ncbi.nlm.nih.gov/pubmed/31289203
http://dx.doi.org/10.3324/haematol.2019.218289