DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts

Telomerase is a ribonucleoprotein complex that maintains the length and integrity of telomeres, and thereby enables cellular proliferation. Understanding the regulation of telomerase in hematopoietic cells is relevant to the pathogenesis of leukemia, in which telomerase is constitutively activated,...

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Detalles Bibliográficos
Autores principales: Richards, Laura A., Kumari, Ashu, Knezevic, Kathy, Thoms, Julie AI, von Jonquieres, Georg, Napier, Christine E., Ali, Zara, O’Brien, Rosemary, Marks-Bluth, Jonathon, Maritz, Michelle F., Pickett, Hilda A, Morris, Jonathan, Pimanda, John E., MacKenzie, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271591/
https://www.ncbi.nlm.nih.gov/pubmed/31413099
http://dx.doi.org/10.3324/haematol.2018.215699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271591/
https://www.ncbi.nlm.nih.gov/pubmed/31413099
http://dx.doi.org/10.3324/haematol.2018.215699

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