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DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts
Telomerase is a ribonucleoprotein complex that maintains the length and integrity of telomeres, and thereby enables cellular proliferation. Understanding the regulation of telomerase in hematopoietic cells is relevant to the pathogenesis of leukemia, in which telomerase is constitutively activated,...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ferrata Storti Foundation
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271591/ https://www.ncbi.nlm.nih.gov/pubmed/31413099 http://dx.doi.org/10.3324/haematol.2018.215699 |