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Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients

BACKGROUND: Early administration of the antifibrinolytic drug tranexamic acid reduces death from bleeding in trauma and postpartum haemorrhage. We examined how the effectiveness and safety of antifibrinolytic drugs varies by the baseline risk of death as a result of bleeding. METHODS: We performed a...

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Detalles Bibliográficos
Autores principales: Ageron, Francois-Xavier, Gayet-Ageron, Angele, Ker, Katharine, Coats, Timothy J., Shakur-Still, Haleema, Roberts, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271662/
https://www.ncbi.nlm.nih.gov/pubmed/32199584
http://dx.doi.org/10.1016/j.bja.2020.01.020