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CYP2C9, a Metabolic CYP450s Enzyme, Plays Critical Roles in Activating Ellagic Acid in Human Intestinal Epithelial Cells

BACKGROUND: The metabolic processing of ellagic acid (EA) by cytochrome P450s (CYP450s) expressed in the intestines is unclear. This study aimed to investigate the effects of CYP450s that are highly expressed in HIEC cells on metabolic activity of EA. MATERIAL/METHODS: HIEC cell models expressing 2B...

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Detalles Bibliográficos
Autores principales: Gu, Yang, Hou, Wei, Shen, Xin-yu, Zhuo, Shi-xuan, Zhang, Hao-ran, Ji, Ming-hui, Chen, Mei-juan, Guo, Yuan-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271682/
https://www.ncbi.nlm.nih.gov/pubmed/32453717
http://dx.doi.org/10.12659/MSM.923104