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L-Carnitine Reduces Myocardial Oxidative Stress and Alleviates Myocardial Ischemia-Reperfusion Injury by Activating Nuclear Transcription-Related Factor 2 (Nrf2)/Heme Oxygenase-1 (HO-1) Signaling Pathway

BACKGROUND: Myocardial ischemia-reperfusion injury (IRI) is an important injury mechanism of myocardial infarction. The purpose of this study was to explore the effects of L-carnitine (LC) on myocardial IRI and its mechanism. MATERIAL/METHODS: The IRI model was made by ligating the left anterior des...

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Detalles Bibliográficos
Autores principales: Zhao, Tana, Chen, Shangjun, Wang, Bingxin, Cai, Dongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271686/
https://www.ncbi.nlm.nih.gov/pubmed/32452468
http://dx.doi.org/10.12659/MSM.923251