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κ-opioid receptor agonists may alleviate intestinal damage in cardiopulmonary bypass rats by inhibiting the NF-κB/HIF-1α pathway

The aims of the present study were to investigate the protective effect of a κ-opioid receptor (KOR) agonist on intestinal barrier dysfunction in rats during cardiopulmonary bypass (CPB), as well as to examine the role of NF-κB and the transcription factor hypoxia-inducible factor-1α (HIF-1α) signal...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyan, Sun, Yingjie, Song, Dandan, Diao, Yugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271736/
https://www.ncbi.nlm.nih.gov/pubmed/32509012
http://dx.doi.org/10.3892/etm.2020.8685