Cargando…

κ-opioid receptor agonists may alleviate intestinal damage in cardiopulmonary bypass rats by inhibiting the NF-κB/HIF-1α pathway

The aims of the present study were to investigate the protective effect of a κ-opioid receptor (KOR) agonist on intestinal barrier dysfunction in rats during cardiopulmonary bypass (CPB), as well as to examine the role of NF-κB and the transcription factor hypoxia-inducible factor-1α (HIF-1α) signal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiaoyan, Sun, Yingjie, Song, Dandan, Diao, Yugang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271736/ https://www.ncbi.nlm.nih.gov/pubmed/32509012 http://dx.doi.org/10.3892/etm.2020.8685

Ejemplares similares

α7 nicotinic acetylcholine receptor agonist inhibits the damage of rat hippocampal neurons by TLR4/Myd88/NF-κB signaling pathway during cardiopulmonary bypass
por: Chen, Keyan, et al.
Publicado: (2017)

κ-opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO-1 pathway
por: Fan, Jianing, et al.
Publicado: (2021)

Reversing Postcardiopulmonary Bypass Associated Cognitive Dysfunction Using k-Opioid Receptor Agonists to Regulate Microglial Polarization via the NLRP3/Caspase-1 Pathway
por: Song, Pei, et al.
Publicado: (2021)

κ-Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder by Activating the Ca(2+)/CaMKII/CREB Pathway
por: Ding, Guopeng, et al.
Publicado: (2021)

Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway
por: Li, Xi, et al.
Publicado: (2019)

NF‐κB and HIF crosstalk in immune responses
por: D'Ignazio, Laura, et al.
Publicado: (2015)

κ-Opioid Receptor Agonist U50448H Protects Against Acute Lung Injury in Rats with Cardiopulmonary Bypass via the CAP-NLRP3 Signaling Pathway
por: Gao, Guang-Jie, et al.
Publicado: (2022)

Hypoxia and Inflammation in Cancer, Focus on HIF and NF-κB
por: D’Ignazio, Laura, et al.
Publicado: (2017)

Retracted: κ-Opioid Receptor Agonist U50448H Protects Against Acute Lung Injury in Rats with Cardiopulmonary Bypass via the CAP-NLRP3 Signaling Pathway
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation
por: Gan, Zhongyuan, et al.
Publicado: (2018)

Hydrogen-rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats
por: Song, Dandan, et al.
Publicado: (2018)

Resveratrol alleviates bleomycin-induced pulmonary fibrosis via suppressing HIF-1α and NF-κB expression
por: Wang, Zaiyan, et al.
Publicado: (2021)

Evolutionary Conserved Regulation of HIF-1β by NF-κB
por: van Uden, Patrick, et al.
Publicado: (2011)

Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells
por: Jiang, Yuan, et al.
Publicado: (2015)

Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway
por: Chen, Keyan, et al.
Publicado: (2018)

Protective effect of MiR-146 on renal injury following cardiopulmonary bypass in rats through mediating NF-κB signaling pathway
por: Ma, Hongbo, et al.
Publicado: (2021)

The mechanism of colon tissue damage mediated by HIF-1α/NF-κB/STAT1 in high-altitude environment
por: Cheng, Junfei, et al.
Publicado: (2022)

Anti-nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist
por: Taylor, A M W, et al.
Publicado: (2015)

Latifolin protects against myocardial infarction by alleviating myocardial inflammatory via the HIF-1α/NF-κB/IL-6 pathway
por: Lai, Xiao-Xiao, et al.
Publicado: (2020)

α7 nicotinic acetylcholine receptor agonist attenuates the cerebral injury in a rat model of cardiopulmonary bypass by activating the Akt/GSK3β pathway
por: Sun, Yingjie, et al.
Publicado: (2017)

Opioids in cancer: The κ-opioid receptor
por: Zhou, Qier, et al.
Publicado: (2022)

XueFu ZhuYu Decoction Alleviates Cardiopulmonary Bypass-Induced NLRP3 Inflammasome-Dependent Pyroptosis by Inhibiting IkB-α/NF-κB Pathway in Acute Lung Injury Rats
por: Li, Hui, et al.
Publicado: (2022)

Hepatocyte cannabinoid 1 receptor nullification alleviates toxin-induced liver damage via NF-κB signaling
por: Kim, Yoo, et al.
Publicado: (2020)

Dietary Curcumin Alleviated Acute Ileum Damage of Ducks (Anas platyrhynchos) Induced by AFB1 through Regulating Nrf2-ARE and NF-κB Signaling Pathways
por: Jin, Sanjun, et al.
Publicado: (2021)

Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway
por: Kim, Hee Jung, et al.
Publicado: (2013)

ERβ regulation of NF-κB activation in prostate cancer is mediated by HIF-1
por: Mak, Paul, et al.
Publicado: (2015)

TLR4 Agonist and Hypoxia Synergistically Promote the Formation of TLR4/NF-κB/HIF-1α Loop in Human Epithelial Ovarian Cancer
por: Zhao, Bin, et al.
Publicado: (2022)

Parecoxib sodium alleviates ischemia reperfusion‐induced pulmonary injury via inhibiting ERK/NF‐κB and further activating the HIF‐1α pathway
por: Guo, Jiantao, et al.
Publicado: (2022)

Tussilagone protects acute lung injury from PM2.5 via alleviating Hif‐1α/NF‐κB‐mediated inflammatory response
por: Lin, Hongwei, et al.
Publicado: (2022)

NF-κB and the Immunoglobulin κ Gene Enhancer
por: Sen, Ranjan
Publicado: (2004)

Enantiomerically Pure Quinoline‐Based κ‐Opioid Receptor Agonists: Chemoenzymatic Synthesis and Pharmacological Evaluation
por: Martin, Benedikt, et al.
Publicado: (2020)

Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects
por: Santino, Federica, et al.
Publicado: (2023)

Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity
por: Walmsley, Sarah R., et al.
Publicado: (2005)

TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway
por: D’Ignazio, Laura, et al.
Publicado: (2018)

Alpinetin inhibits breast cancer growth by ROS/NF‐κB/HIF‐1α axis
por: Zhang, Tao, et al.
Publicado: (2020)

DNA damage independent inhibition of NF-κB transcription by anthracyclines
por: Chora, Angelo Ferreira, et al.
Publicado: (2022)

BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery
por: Xiao, Wei, et al.
Publicado: (2021)

Alpha-7 nicotinic acetylcholine receptor agonist alleviates psoriasis-like inflammation through inhibition of the STAT3 and NF-κB signaling pathway
por: Chen, Yiwen, et al.
Publicado: (2022)

Salidroside Alleviates Cartilage Degeneration Through NF-κB Pathway in Osteoarthritis Rats
por: Gao, Hui, et al.
Publicado: (2020)

Oxycodone Alleviates Endometrial Injury via the TLR4/NF-κB Pathway
por: Zhu, Aibing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_99grds01iuorgmih8gcc934nr6