A baculoviral system for the production of human β-glucocerebrosidase enables atomic resolution analysis

The lysosomal glycoside hydrolase β-glucocerebrosidase (GBA; sometimes called GBA1 or GC(ase)) catalyses the hydrolysis of glycosphingolipids. Inherited deficiencies in GBA cause the lysosomal storage disorder Gaucher disease (GD). Consequently, GBA is of considerable medical interest, with continuo...

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Detalles Bibliográficos
Autores principales: Rowland, Rhianna J., Wu, Liang, Liu, Feng, Davies, Gideon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271948/
https://www.ncbi.nlm.nih.gov/pubmed/32496218
http://dx.doi.org/10.1107/S205979832000501X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271948/
https://www.ncbi.nlm.nih.gov/pubmed/32496218
http://dx.doi.org/10.1107/S205979832000501X

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