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Structural analysis of the PATZ1 BTB domain homodimer

PATZ1 is a ubiquitously expressed transcriptional repressor belonging to the ZBTB family that is functionally expressed in T lymphocytes. PATZ1 targets the CD8 gene in lymphocyte development and interacts with the p53 protein to control genes that are important in proliferation and in the DNA-damage...

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Detalles Bibliográficos
Autores principales: Piepoli, Sofia, Alt, Aaron Oliver, Atilgan, Canan, Mancini, Erika Jazmin, Erman, Batu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271949/
https://www.ncbi.nlm.nih.gov/pubmed/32496219
http://dx.doi.org/10.1107/S2059798320005355