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Atomistic mechanism of transmembrane helix association

Transmembrane helix association is a fundamental step in the folding of helical membrane proteins. The prototypical example of this association is formation of the glycophorin dimer. While its structure and stability have been well-characterized experimentally, the detailed assembly mechanism is har...

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Detalles Bibliográficos
Autores principales: Domański, Jan, Sansom, Mark S. P., Stansfeld, Phillip J., Best, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272003/
https://www.ncbi.nlm.nih.gov/pubmed/32497094
http://dx.doi.org/10.1371/journal.pcbi.1007919