siRNA inhibition and not chemical inhibition of Suv39h1/2 enhances pre-implantation embryonic development of bovine somatic cell nuclear transfer embryos

The efficiency of somatic cell nuclear transfer (SCNT) is low due to the strong resistance of somatic donor cells to epigenetic reprogramming. Many epigenetic drugs targeting DNA methylation and histone acetylation have been used in attempts to improve the in vitro and in vivo development of SCNT em...

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Detalles Bibliográficos
Autores principales: Jafarpour, Farnoosh, Ghazvini Zadegan, Faezeh, Ostadhosseini, Somayyeh, Hajian, Mehdi, Kiani-Esfahani, Abbas, Nasr-Esfahani, M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272017/
https://www.ncbi.nlm.nih.gov/pubmed/32497112
http://dx.doi.org/10.1371/journal.pone.0233880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272017/
https://www.ncbi.nlm.nih.gov/pubmed/32497112
http://dx.doi.org/10.1371/journal.pone.0233880

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