Development of immortalized human hepatocyte-like hybrid cells by fusion of multi-lineage progenitor cells with primary hepatocytes

Human primary hepatocytes (PHs) are critical to studying liver functions, drug metabolism and toxicity. PHs isolated from livers that are unacceptable for transplantation have limited expansion and culture viability in vitro, in addition to rapidly deteriorating enzymatic functions. The unsuitabilit...

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Detalles Bibliográficos
Autores principales: Collins, Daniel P., Hapke, Joel H., Aravalli, Rajagopal N., Steer, Clifford J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272032/
https://www.ncbi.nlm.nih.gov/pubmed/32497071
http://dx.doi.org/10.1371/journal.pone.0234002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272032/
https://www.ncbi.nlm.nih.gov/pubmed/32497071
http://dx.doi.org/10.1371/journal.pone.0234002

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