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Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex

The B7 family represents one of the best-studied subgroups within the Ig superfamily, yet new interactions continue to be discovered. However, this binding promiscuity represents a major challenge for defining the biological contribution of each specific interaction. We developed a strategy for addr...

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Detalles Bibliográficos
Autores principales: Garrett-Thomson, Sarah C., Massimi, Aldo, Fedorov, Elena V., Bonanno, Jeffrey B., Scandiuzzi, Lisa, Hillerich, Brandan, Seidel, Ronald D., Love, James D., Garforth, Scott J., Guha, Chandan, Almo, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272049/
https://www.ncbi.nlm.nih.gov/pubmed/32497097
http://dx.doi.org/10.1371/journal.pone.0233578