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Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children

Activation of the steroidogenic enzyme CYP11A1 was shown to be necessary for the development of peanut-induced intestinal anaphylaxis and IL-13 production in allergic mice. We determined if levels of CYP11A1 in peripheral blood T cells from peanut-allergic (PA) children compared to non-allergic cont...

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Detalles Bibliográficos
Autores principales: Wang, Meiqin, Strand, Matthew J., Lanser, Bruce J., Santos, Carah, Bendelja, Kreso, Fish, Jennifer, Esterl, Elizabeth A., Ashino, Shigeru, Abbott, Jordan K., Knight, Vijaya, Gelfand, Erwin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272076/
https://www.ncbi.nlm.nih.gov/pubmed/32497050
http://dx.doi.org/10.1371/journal.pone.0233563