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Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children
Activation of the steroidogenic enzyme CYP11A1 was shown to be necessary for the development of peanut-induced intestinal anaphylaxis and IL-13 production in allergic mice. We determined if levels of CYP11A1 in peripheral blood T cells from peanut-allergic (PA) children compared to non-allergic cont...
Autores principales: | Wang, Meiqin, Strand, Matthew J., Lanser, Bruce J., Santos, Carah, Bendelja, Kreso, Fish, Jennifer, Esterl, Elizabeth A., Ashino, Shigeru, Abbott, Jordan K., Knight, Vijaya, Gelfand, Erwin W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272076/ https://www.ncbi.nlm.nih.gov/pubmed/32497050 http://dx.doi.org/10.1371/journal.pone.0233563 |
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