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MicroRNA-674-5p induced by HIF-1α targets XBP-1 in intestinal epithelial cell injury during endotoxemia

Intestinal mucosal integrity dysfunction during endotoxemia can contribute to translocation of intestinal bacteria and a persistent systemic inflammatory response, which both fuel the pathophysiological development of sepsis or endotoxemia. The pathogenesis of intestinal damage induced by endotoxemi...

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Detalles Bibliográficos
Autores principales: Liu, Zhihao, Jiang, Jie, Dai, Weigang, Wei, Hongyan, Zhang, Xiaofei, Yang, Zhen, Xiong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272402/
https://www.ncbi.nlm.nih.gov/pubmed/32550011
http://dx.doi.org/10.1038/s41420-020-0280-5