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Analysis of human metabolism by reducing the complexity of the genome-scale models using redHUMAN

Altered metabolism is associated with many human diseases. Human genome-scale metabolic models (GEMs) were reconstructed within systems biology to study the biochemistry occurring in human cells. However, the complexity of these networks hinders a consistent and concise physiological representation....

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Detalles Bibliográficos
Autores principales: Masid, Maria, Ataman, Meric, Hatzimanikatis, Vassily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272419/
https://www.ncbi.nlm.nih.gov/pubmed/32499584
http://dx.doi.org/10.1038/s41467-020-16549-2