Cargando…
Analysis of human metabolism by reducing the complexity of the genome-scale models using redHUMAN
Altered metabolism is associated with many human diseases. Human genome-scale metabolic models (GEMs) were reconstructed within systems biology to study the biochemistry occurring in human cells. However, the complexity of these networks hinders a consistent and concise physiological representation....
Autores principales: | Masid, Maria, Ataman, Meric, Hatzimanikatis, Vassily |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272419/ https://www.ncbi.nlm.nih.gov/pubmed/32499584 http://dx.doi.org/10.1038/s41467-020-16549-2 |
Ejemplares similares
-
Author Correction: Analysis of human metabolism by reducing the complexity of the genome-scale models using redHUMAN
por: Masid, Maria, et al.
Publicado: (2020) -
redGEM: Systematic reduction and analysis of genome-scale metabolic reconstructions for development of consistent core metabolic models
por: Ataman, Meric, et al.
Publicado: (2017) -
A genome-scale metabolic model of Saccharomyces cerevisiae that integrates expression constraints and reaction thermodynamics
por: Oftadeh, Omid, et al.
Publicado: (2021) -
Modeling metabolic networks of individual bacterial agents in heterogeneous and dynamic soil habitats (IndiMeSH)
por: Borer, Benedict, et al.
Publicado: (2019) -
lumpGEM: Systematic generation of subnetworks and elementally balanced lumped reactions for the biosynthesis of target metabolites
por: Ataman, Meric, et al.
Publicado: (2017)