Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion

Tetraploidy, a common feature in cancer, results in the presence of extra centrosomes, which has been associated with chromosome instability (CIN) and aneuploidy. Deregulation in the number of centrosomes triggers tumorigenesis. However, how supernumerary centrosomes evolve during the emergence of t...

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Detalles Bibliográficos
Autores principales: Galofré, Claudia, Asensio, Elena, Ubach, Maria, Torres, Irianna M., Quintanilla, Isabel, Castells, Antoni, Camps, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272426/
https://www.ncbi.nlm.nih.gov/pubmed/32499568
http://dx.doi.org/10.1038/s41598-020-65975-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272426/
https://www.ncbi.nlm.nih.gov/pubmed/32499568
http://dx.doi.org/10.1038/s41598-020-65975-1

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