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Amyloid Aggregation of Insulin: An Interaction Study of Green Tea Constituents

Exogenous insulin, used as a therapeutic agent for diabetes, forms insoluble deposits containing amyloid fibrillar structures near the administration site. We have analyzed the in vitro anti-amyloid activity of four green tea constituents: (-)-epigallocatechin gallate (EGCG), (-)-epicatechin (EC), g...

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Detalles Bibliográficos
Autores principales: Gancar, Miroslav, Kurin, Elena, Bednarikova, Zuzana, Marek, Jozef, Mucaji, Pavel, Nagy, Milan, Gazova, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272432/
https://www.ncbi.nlm.nih.gov/pubmed/32499589
http://dx.doi.org/10.1038/s41598-020-66033-6