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Integrated analysis of the molecular pathogenesis of FDXR-associated disease

The mitochondrial flavoprotein ferredoxin reductase (FDXR) is required for biogenesis of iron–sulfur clusters and for steroidogenesis. Iron–sulfur (Fe–S) clusters are ubiquitous cofactors essential to various cellular processes, and an increasing number of disorders are associated with disruptions i...

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Detalles Bibliográficos
Autores principales: Slone, Jesse D., Yang, Li, Peng, Yanyan, Queme, Luis F., Harris, Belinda, Rizzo, Stacey J. Sukoff, Green, Torrian, Ryan, Jennifer L., Jankowski, Michael P., Reinholdt, Laura G., Huang, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272433/
https://www.ncbi.nlm.nih.gov/pubmed/32499495
http://dx.doi.org/10.1038/s41419-020-2637-3