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Structural and functional evidence of bacterial antiphage protection by Thoeris defense system via NAD(+) degradation

The intense arms race between bacteria and phages has led to the development of diverse antiphage defense systems in bacteria. Unlike well-known restriction-modification and CRISPR-Cas systems, recently discovered systems are poorly characterized. One such system is the Thoeris defense system, which...

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Detalles Bibliográficos
Autores principales: Ka, Donghyun, Oh, Hyejin, Park, Eunyoung, Kim, Jeong-Han, Bae, Euiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272460/
https://www.ncbi.nlm.nih.gov/pubmed/32499527
http://dx.doi.org/10.1038/s41467-020-16703-w