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S92 phosphorylation induces structural changes in the N-terminus domain of human mitochondrial calcium uniporter

The mitochondrial calcium uniporter (MCU) plays essential roles in mitochondrial calcium homeostasis and regulates cellular functions, such as energy synthesis, cell growth, and development. Thus, MCU activity is tightly controlled by its regulators as well as post-translational modification, includ...

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Detalles Bibliográficos
Autores principales: Lee, Youngjin, Park, Jongseo, Lee, Gihwan, Yoon, Sanghwa, Min, Choon Kee, Kim, Tae Gyun, Yamamoto, Takenori, Kim, Do Han, Lee, Keun Woo, Eom, Soo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272466/
https://www.ncbi.nlm.nih.gov/pubmed/32499574
http://dx.doi.org/10.1038/s41598-020-65994-y