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Prescribed Doses of CYP2D6-Metabolized Drugs and Hemodynamic Responses in Relation to CYP2D6 Genotype Among Older Patients Exposed to Polypharmacy

BACKGROUND: Many drugs with dose-dependent effects on hemodynamic variables are metabolized by cytochrome P450 2D6 (CYP2D6). The aim of this study was to compare prescribed dosages and hemodynamic responses of such drugs in relation to pharmacogenetic variability in CYP2D6 metabolism among patients...

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Detalles Bibliográficos
Autores principales: Romskaug, Rita, Wyller, Torgeir Bruun, Straand, Jørund, Kersten, Hege, Molden, Espen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272489/
https://www.ncbi.nlm.nih.gov/pubmed/32346827
http://dx.doi.org/10.1007/s40266-020-00763-0