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The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation

In eukaryotes, trimethylation of lysine 9 on histone H3 (H3K9) is associated with transcriptional silencing of transposable elements (TEs). In drosophila ovaries, this heterochromatic repressive mark is thought to be deposited by SetDB1 on TE genomic loci after the initial recognition of nascent tra...

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Detalles Bibliográficos
Autores principales: Mugat, Bruno, Nicot, Simon, Varela-Chavez, Carolina, Jourdan, Christophe, Sato, Kaoru, Basyuk, Eugenia, Juge, François, Siomi, Mikiko C., Pélisson, Alain, Chambeyron, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272611/
https://www.ncbi.nlm.nih.gov/pubmed/32499524
http://dx.doi.org/10.1038/s41467-020-16635-5