Cargando…

The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ

Colorectal cancer is a devastating disease with a low 5-year survival rate. Recently, many researchers have studied the mechanisms of tumor progression related to the tumor microenvironment. Here, we addressed the prognostic value of tumor-associated macrophages (TAMs) using a total of 232 CRC patie...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Yeo Song, Song, Su Jeong, Hong, Hye Kyung, Oh, Bo Young, Lee, Woo Yong, Cho, Yong Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272616/
https://www.ncbi.nlm.nih.gov/pubmed/32444799
http://dx.doi.org/10.1038/s12276-020-0436-7