A novel, rationally designed, hybrid antimicrobial peptide, inspired by cathelicidin and aurein, exhibits membrane-active mechanisms against Pseudomonas aeruginosa

Antimicrobial peptides (AMPs) are promising alternatives to classical antibiotics for the treatment of drug-resistant infections. Due to their versatility and unlimited sequence space, AMPs can be rationally designed by modulating physicochemical determinants to favor desired biological parameters a...

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Detalles Bibliográficos
Autores principales: Klubthawee, Natthaporn, Adisakwattana, Poom, Hanpithakpong, Warunee, Somsri, Sangdao, Aunpad, Ratchaneewan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272617/
https://www.ncbi.nlm.nih.gov/pubmed/32499514
http://dx.doi.org/10.1038/s41598-020-65688-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272617/
https://www.ncbi.nlm.nih.gov/pubmed/32499514
http://dx.doi.org/10.1038/s41598-020-65688-5

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