Gene expression regulation by CDK12: a versatile kinase in cancer with functions beyond CTD phosphorylation

Cyclin-dependent kinases (CDKs) play critical roles in cell cycle progression and gene expression regulation. In human cancer, transcription-associated CDKs can activate oncogenic gene expression programs, whereas cell cycle-regulatory CDKs mainly induce uncontrolled proliferation. Cyclin-dependent...

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Detalles Bibliográficos
Autores principales: Choi, Seung Hyuk, Kim, Seongjae, Jones, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272620/
https://www.ncbi.nlm.nih.gov/pubmed/32451425
http://dx.doi.org/10.1038/s12276-020-0442-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272620/
https://www.ncbi.nlm.nih.gov/pubmed/32451425
http://dx.doi.org/10.1038/s12276-020-0442-9

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