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Gene expression regulation by CDK12: a versatile kinase in cancer with functions beyond CTD phosphorylation
Cyclin-dependent kinases (CDKs) play critical roles in cell cycle progression and gene expression regulation. In human cancer, transcription-associated CDKs can activate oncogenic gene expression programs, whereas cell cycle-regulatory CDKs mainly induce uncontrolled proliferation. Cyclin-dependent...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272620/ https://www.ncbi.nlm.nih.gov/pubmed/32451425 http://dx.doi.org/10.1038/s12276-020-0442-9 |