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Liquid-liquid phase separation induces pathogenic tau conformations in vitro

Formation of membrane-less organelles via liquid-liquid phase separation is one way cells meet the biological requirement for spatiotemporal regulation of cellular components and reactions. Recently, tau, a protein known for its involvement in Alzheimer’s disease and other tauopathies, was found to...

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Detalles Bibliográficos
Autores principales: Kanaan, Nicholas M., Hamel, Chelsey, Grabinski, Tessa, Combs, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272632/
https://www.ncbi.nlm.nih.gov/pubmed/32499559
http://dx.doi.org/10.1038/s41467-020-16580-3