Cellular Fibronectin Containing Extra Domain A Causes Insulin Resistance via Toll-like Receptor 4

We determined the role of cellular fibronectin (CFN) containing the alternatively spliced extra domain A (FN-EDA) in causing insulin resistance (IR) through toll-like receptor 4 (TLR4). Circulating FN-EDA level was evaluated in mouse and rat IR models. Specific anti-FN-EDA antibody and TLR4 inhibito...

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Detalles Bibliográficos
Autores principales: Rajak, Sangam, Hussain, Yusuf, Singh, Khushboo, Tiwari, Swasti, Ahmad, Basir, Bharti, Sachi, Prakash, Prem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272645/
https://www.ncbi.nlm.nih.gov/pubmed/32499562
http://dx.doi.org/10.1038/s41598-020-65970-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272645/
https://www.ncbi.nlm.nih.gov/pubmed/32499562
http://dx.doi.org/10.1038/s41598-020-65970-6

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