α-Synuclein-112 Impairs Synaptic Vesicle Recycling Consistent With Its Enhanced Membrane Binding Properties

Synucleinopathies are neurological disorders associated with α-synuclein overexpression and aggregation. While it is well-established that overexpression of wild type α-synuclein (α-syn-140) leads to cellular toxicity and neurodegeneration, much less is known about other naturally occurring α-synucl...

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Detalles Bibliográficos
Autores principales: Soll, Lindsey G., Eisen, Julia N., Vargas, Karina J., Medeiros, Audrey T., Hammar, Katherine M., Morgan, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272675/
https://www.ncbi.nlm.nih.gov/pubmed/32548120
http://dx.doi.org/10.3389/fcell.2020.00405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272675/
https://www.ncbi.nlm.nih.gov/pubmed/32548120
http://dx.doi.org/10.3389/fcell.2020.00405

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