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α-Synuclein-112 Impairs Synaptic Vesicle Recycling Consistent With Its Enhanced Membrane Binding Properties
Synucleinopathies are neurological disorders associated with α-synuclein overexpression and aggregation. While it is well-established that overexpression of wild type α-synuclein (α-syn-140) leads to cellular toxicity and neurodegeneration, much less is known about other naturally occurring α-synucl...
Autores principales: | Soll, Lindsey G., Eisen, Julia N., Vargas, Karina J., Medeiros, Audrey T., Hammar, Katherine M., Morgan, Jennifer R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272675/ https://www.ncbi.nlm.nih.gov/pubmed/32548120 http://dx.doi.org/10.3389/fcell.2020.00405 |
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